Regenokine® Therapy in Scottsdale: Arizona's Exclusive Provider
Unlock your Natural Healing Power
Dr. Ashu Goyle is one of only nine physicians in the United States—and the only doctor in Arizona—offering the Regenokine® Program. This innovative autologous treatment uses your own blood to create a serum concentrated with anti-inflammatory proteins, targeting inflammation at its source.
Regenokine® is the treatment professional athletes like the late Kobe Bryant famously used to return to competition. Now available in Scottsdale through Integrated Spine, Pain & Wellness, this exclusive therapy offers patients an advanced option for addressing joint and back discomfort using their own biological materials.
What Is Regenokine®?
Regenokine® is an autologous conditioned serum (ACS) therapy developed in Germany. The treatment processes your own blood to concentrate naturally occurring anti-inflammatory proteins—specifically Interleukin-1 Receptor Antagonist (IL-1Ra)—which may help modulate inflammatory responses in joints and soft tissues.
How It Works:
Your blood is drawn and incubated under specific conditions that stimulate the production of anti-inflammatory proteins. The serum is then processed to concentrate these beneficial proteins while filtering out pro-inflammatory components. The resulting autologous conditioned serum is injected into the affected joint or area.
What Makes Regenokine® Different:
Unlike treatments that suppress all inflammation (like cortisone), Regenokine® delivers concentrated anti-inflammatory proteins that may help rebalance the joint environment. And unlike third-party products, Regenokine® uses only your own blood—you know exactly what you’re receiving.
Key Points:
- Autologous: Uses your own blood, not donor products
- Concentrated anti-inflammatory proteins: Specifically targets inflammatory mediators
- Developed in Germany: Established treatment protocol with documented use by professional athletes
- Exclusive availability: Only 9 providers in the United States; Dr. Goyle is the only provider in Arizona
The Kobe Bryant Connection
Regenokine® gained international attention when NBA legend Kobe Bryant traveled to Germany for treatment in 2011. Facing chronic knee pain that threatened his career, Bryant underwent the Regenokine® protocol and returned to elite competition.
Bryant wasn’t alone—numerous professional athletes from the NFL, MLB, and international sports have sought Regenokine® therapy. The treatment’s appeal to elite athletes lies in its use of the patient’s own biological materials and its focus on addressing inflammation rather than simply masking symptoms.
Now, you don’t have to travel to Germany. Dr. Goyle brings this exclusive treatment to Scottsdale as one of only nine certified Regenokine® providers in the country.
Why Regenokine® May Be Worth Considering
Targets Inflammation at Its Source
Chronic joint discomfort often involves ongoing inflammatory processes. Interleukin-1 (IL-1) is a key inflammatory mediator that contributes to cartilage breakdown and joint discomfort. Regenokine® concentrates your body’s natural IL-1 Receptor Antagonist (IL-1Ra), which may help modulate this inflammatory response.
Uses Your Own Biological Materials
Like all regenerative treatments at ISPW, Regenokine® is autologous—it uses your own blood. There are no donor products, no third-party materials, and no rejection risk. You know exactly what’s being injected.
Different Mechanism Than Other Treatments
Regenokine® works differently than cortisone, PRP, or stem cell therapy:
- Cortisone: Broadly suppresses inflammation but may have diminishing returns with repeated use
- PRP: Concentrates platelets and growth factors from your blood
- BMAC: Delivers your own bone marrow stem cells plus growth factors
- Regenokine®: Specifically concentrates anti-inflammatory proteins (IL-1Ra) from your blood
This unique mechanism means Regenokine® may be appropriate for patients who haven’t responded adequately to other approaches, or it may be used in combination with other regenerative treatments.
Favorable Treatment Experience
The Regenokine® protocol typically involves a series of injections over several days, allowing for concentrated treatment. Many patients appreciate the focused treatment approach and the knowledge that they’re receiving a therapy trusted by world-class athletes.
Who May Be a Good Candidate for Regenokine®?
Regenokine® may be worth considering for patients with:
Joint Conditions:
- Knee discomfort and osteoarthritis symptoms
- Hip pain
- Shoulder issues
- Ankle, elbow, and wrist conditions
Spine-Related Concerns:
- Chronic back pain
- Neck discomfort
- Facet joint issues
Characteristics of Potential Candidates:
- Mild to moderate joint or spine conditions
- Chronic discomfort that hasn’t responded adequately to conservative treatments
- Interest in autologous (your own cells) approaches
- Realistic expectations about gradual improvement
- Overall good health
Who May Not Be Ideal Candidates:
- Advanced, end-stage arthritis requiring joint replacement
- Active infections
- Certain blood disorders
- Those expecting immediate or guaranteed results
During your consultation, Dr. Goyle will evaluate your specific situation and provide honest guidance about whether Regenokine® may be appropriate for you.
The Regenokine® Treatment Process
Step 1: Consultation and Evaluation
Your journey begins with a comprehensive consultation with Dr. Goyle. He’ll review your medical history, examine the affected area, discuss your symptoms and goals, and determine whether Regenokine® may be appropriate. We believe in honest conversations—not every patient is a candidate for every treatment.
Step 2: Blood Collection
If you proceed with treatment, a sample of your blood is drawn. This blood is then incubated under specific conditions that stimulate production of anti-inflammatory proteins.
Step 3: Processing
Your blood is processed to concentrate the beneficial anti-inflammatory proteins (particularly IL-1Ra) while separating out pro-inflammatory components. The result is your personalized autologous conditioned serum.
Step 4: Injection Series
Using advanced image guidance (fluoroscopy or ultrasound), Dr. Goyle precisely delivers the Regenokine® serum to the target area. The treatment typically involves a series of injections to deliver the concentrated anti-inflammatory proteins.
Step 5: Follow-Up Care
We monitor your progress through follow-up appointments, adjusting your care plan as needed. The body’s response develops gradually over weeks to months.
What Results Can You Realistically Expect?
Setting Appropriate Expectations:
Regenokine® may help address inflammatory processes in joints and soft tissues. However, it’s important to understand:
- Gradual response: Changes develop over weeks to months, not days
- Variable outcomes: Individual responses differ based on condition severity, overall health, and other factors
- Not a cure: Regenokine® may help manage symptoms and support joint health, but it doesn’t reverse arthritis or regrow cartilage
- Part of comprehensive care: Best results often come when combined with appropriate activity modification, physical therapy, and lifestyle factors
What Regenokine® Cannot Do:
- Guarantee specific outcomes
- Replace joint replacement surgery when it’s clearly indicated
- Cure arthritis or other degenerative conditions
- Provide immediate relief
Dr. Goyle will provide honest guidance about what’s realistic for your specific situation.
How Regenokine® Compares to Other Treatments
Understanding your options helps you make informed decisions:
Treatment | Source | Mechanism | Best For |
Regenokine® | Your own blood | Concentrated anti-inflammatory proteins (IL-1Ra) | Inflammation-driven joint/back discomfort |
PRP | Your own blood | Concentrated platelets and growth factors | Soft tissue injuries, mild joint conditions |
BMAC | Your own bone marrow | Mesenchymal stem cells plus growth factors | Joint conditions, disc-related issues |
Cortisone | Synthetic steroid | Broad anti-inflammatory suppression | Acute inflammation, short-term relief |
MLS M7 Laser | Light energy | Supports natural processes, addresses inflammation | Complementary therapy, soft tissue |
During your consultation, Dr. Goyle will discuss which approach—or combination—may be most appropriate for your goals.
Our Complete Regenerative Medicine Approach
Regenokine® is one component of our comprehensive regenerative offerings. Depending on your situation, Dr. Goyle may recommend Regenokine® alone or in combination with other treatments:
Bone Marrow Aspirate Concentrate (BMAC)
Your own bone marrow stem cells, harvested from your hip, processed in our office, and delivered the same day. BMAC provides mesenchymal stem cells along with growth factors—all from your own body. No third-party donors, no lab culturing, no rejection risk.
Platelet-Rich Plasma (PRP)
Your own blood, processed to concentrate platelets and their associated growth factors. Using the APEX Biologix system for superior concentration, PRP can be used alone or in combination with other regenerative therapies.
MLS M7 Class IV Laser Therapy
State-of-the-art therapeutic laser technology that delivers light energy to support the body’s natural processes. Non-invasive with no downtime, the MLS laser can complement regenerative injections.
Interventional Procedures
For acute situations, we also offer:
- Epidural steroid injections (positioned as short-term bridge treatment)
- Facet joint injections
- Trigger point injections
- Medial branch blocks
All injection-based treatments are performed using advanced image guidance (fluoroscopy or ultrasound) to ensure precision.
Why Choose Dr. Goyle for Regenokine®
Exclusive Access
Dr. Goyle is one of only nine physicians in the United States certified to offer Regenokine®—and the only provider in Arizona. Patients throughout the Southwest no longer need to travel out of state (or to Germany) for this exclusive treatment.
Cleveland Clinic Training
Dr. Goyle completed his fellowship at the Cleveland Clinic—one of the nation’s premier medical institutions. This rigorous training with world leaders in pain medicine provided expertise in both interventional procedures and regenerative approaches.
Double Board Certification
Board-certified in both anesthesiology and interventional pain management, Dr. Goyle demonstrates advanced competency in precise, image-guided procedures.
Autologous-Only Philosophy
ISPW uses only autologous treatments—your own biological materials. We don’t use third-party donor products, umbilical cord tissue, or commercial exosome products. With Regenokine®, PRP, and BMAC, you always know exactly what you’re receiving.
Image-Guided Precision
Every injection is performed under fluoroscopy or ultrasound guidance, ensuring accurate delivery to the target area.
Phoenix Magazine “Top Doc”
Dr. Goyle has been recognized as a Phoenix Magazine “Top Doc” from 2011-2020, reflecting his commitment to excellent patient care.
The Concierge Experience
Regenokine® therapy at Integrated Spine, Pain & Wellness reflects our concierge approach to pain medicine:
- Personalized attention: Extended consultation time with Dr. Goyle—not rushed, assembly-line care
- Direct access: Responsive communication throughout your treatment journey
- Comprehensive evaluation: Thorough assessment of your condition and goals
- Honest guidance: Realistic expectations, not overselling
- Coordinated care: Treatment plans tailored to your specific needs
- Follow-up support: Ongoing monitoring of your progress
This approach reflects our belief that advanced regenerative medicine deserves more than a transactional experience. You deserve expertise, time, and attention focused on your care.
Is Regenokine® Right for You?
The best way to determine whether Regenokine® is appropriate for your situation is a consultation with Dr. Goyle.
During your consultation, we’ll:
- Review your condition, imaging, and medical history
- Discuss your symptoms, goals, and previous treatments
- Evaluate whether Regenokine®, another regenerative approach, or a combination may be appropriate
- Provide honest guidance and realistic expectations
- Answer all your questions
If Regenokine® isn’t the right fit for your situation, Dr. Goyle will recommend alternatives—whether that’s another regenerative option, interventional procedures, or surgical consultation.
Schedule Your Consultation
Experience the treatment that world-class athletes have sought—now available in Scottsdale through Arizona’s only Regenokine® provider.
Don’t let joint or back discomfort limit your quality of life. Discover whether Regenokine® or another regenerative approach may help you get back to the activities you love.
Contact Integrated Spine, Pain & Wellness today to schedule your consultation with Dr. Goyle.
Dr. Ashu Goyle is the founder of Integrated Spine, Pain & Wellness in Scottsdale, Arizona. Double board-certified in anesthesiology and interventional pain management with fellowship training from the Cleveland Clinic, he is one of only nine Regenokine® providers in the United States—and the only provider in Arizona.
ARE YOU THE
Ideal Candidate?
If you’re an active person struggling with pain that limits your physical activities, PRP therapy may be the solution you’re seeking. It’s designed for those who want to address the root cause of their pain, not just mask symptoms. Whether it’s chronic back pain, chronic tendonitis, knee pain, or a lingering sports injury, PRP therapy may offer a path to recovery that aligns with your body’s natural healing processes.
Why Trust Dr. Goyle with Your Recovery?
Dr. Goyle stands out as a distinguished expert in regenerative medicine and orthobiologics, backed by an impressive foundation of training and experience. His journey in anesthesiology and pain management was honed at the prestigious Cleveland Clinic, a testament to his commitment to excellence in patient care. With double board certifications in anesthesiology and pain medicine, along with a rich background in research and various certifications in regenerative treatments, Dr. Goyle offers a depth of expertise that is rare in the field. He crafts personalized treatment plans aimed at active individuals, prioritizing the restoration of function and a swift return to the activities and lifestyles his patients cherish.
RECLAIM YOUR
Active Life with PRP Therapy
Don’t let pain keep you on the sidelines. Discover how PRP therapy may help you overcome injury, reduce pain, and enhance your body’s ability to heal—so you can return to the active lifestyle you cherish.
Get Started on Your Path to Recovery
Reach out to book your complimentary discovery call. This is your opportunity to explore how PRP therapy might be the natural and effective solution you need to maintain your active lifestyle.
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OUR COMMITMENT TO EXCELLENCE
Accreditations & Partnerships
The Interventional Orthobiologics Foundation
Institute For Functional Medicine
Cleveland Clinic
The American Board of Anesthesiologists
American Society of Anesthesiologists
American Society of Regional Anesthesia and Pain Medicine
American Society of Interventional Pain Physicians
The American Academy of Anti-Aging Medicine
Top Doctors
Discover the Science Behind Regenerative Medicine
As you consider regenerative medicine, you may be curious about the science that supports its effectiveness.
Our goal is to provide you with credible data and clinical studies that showcase how regenerative medicine works, so you can make an informed choice about your health.
Frequently Asked Questions
What is Regenokine®?
Regenokine® is an autologous conditioned serum (ACS) therapy that processes your own blood to concentrate anti-inflammatory proteins, particularly Interleukin-1 Receptor Antagonist (IL-1Ra). These proteins may help modulate inflammatory responses in joints and soft tissues. The treatment was developed in Germany and gained attention when professional athletes like the late Kobe Bryant used it.
Why is Regenokine® so exclusive?
Regenokine® requires specific certification and training. Only nine physicians in the United States are certified to offer this treatment. Dr. Goyle is the only certified Regenokine® provider in Arizona, bringing this exclusive therapy to Scottsdale patients who would otherwise need to travel out of state or internationally.
How is Regenokine® different from cortisone injections?
Cortisone is a synthetic steroid that broadly suppresses inflammation. Regenokine® uses your own blood, processed to concentrate your body’s natural anti-inflammatory proteins. Rather than suppressing all inflammation, Regenokine® delivers concentrated IL-1Ra that may help rebalance the inflammatory environment in your joint. Additionally, repeated cortisone injections may have diminishing returns, while Regenokine® uses your own biological materials.
How is Regenokine® different from PRP or stem cell therapy?
Each treatment has a different mechanism:
- Regenokine® concentrates anti-inflammatory proteins (IL-1Ra) from your blood
- PRP concentrates platelets and growth factors from your blood
- BMAC (stem cell therapy) delivers mesenchymal stem cells plus growth factors from your bone marrow
All three are autologous (using your own biological materials). Dr. Goyle can discuss which approach—or combination—may be most appropriate for your situation.
Did Kobe Bryant really use Regenokine®?
Yes. In 2011, Kobe Bryant traveled to Germany for Regenokine® treatment for chronic knee issues. He was among several professional athletes who sought this therapy. His experience helped bring international attention to Regenokine® as an option for athletes and active individuals dealing with joint discomfort.
How long until I might notice changes?
The body’s response to Regenokine® develops gradually over weeks to months. This isn’t a quick fix like cortisone—it’s supporting your body’s natural processes. Individual timelines vary, and not all patients experience the same degree of benefit. Dr. Goyle will discuss realistic expectations during your consultation.
Is Regenokine® FDA approved?
Regenokine® is an autologous blood product—it uses your own blood processed the same day. The FDA regulates medical devices and drugs differently than autologous procedures. Dr. Goyle follows established protocols and uses your own biological materials, which eliminates concerns about third-party product quality or rejection risk.
How much does Regenokine® cost?
Regenokine® requires out-of-pocket payment, as it’s not typically covered by insurance. The investment reflects the exclusivity of the treatment, Dr. Goyle’s specialized certification, and the comprehensive care you receive. During your consultation, we’ll discuss specific costs based on your treatment plan.
Can Regenokine® be combined with other treatments?
Yes. Depending on your situation, Dr. Goyle may recommend Regenokine® alone or in combination with other regenerative approaches like PRP or BMAC. He’ll evaluate your condition and goals to determine the most appropriate approach.
What conditions do you address with Regenokine®?
We focus on musculoskeletal conditions: joint discomfort (knee, hip, shoulder), spine-related issues (back pain, neck discomfort), and soft tissue concerns. Regenokine® is not appropriate for systemic conditions, neurological disorders, or advanced end-stage arthritis requiring joint replacement.
